Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.47 |
| ▸ | MMP9 | P14780 | 9/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818486 | 0.88 | MMP2 (0.44) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL7715008 | 0.82 | LTA4H (0.55) | ALDH1A1KDM4ENPSR1RXFP1NPC1 | |
| SCHEMBL6820161 | 0.78 | LTA4H (0.55) | ALDH1A1KDM4ENPSR1RXFP1NPC1 | |
| SCHEMBL6820163 | 0.78 | LTA4H (0.55) | ALDH1A1KDM4ENPSR1RXFP1NPC1 | |
| SCHEMBL2179155 | 0.78 | KDM4E (0.51) | MMP2ALDH1A1L3MBTL1KDM4ENPSR1 | |
| SCHEMBL6814135 | 0.76 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9185732 | 0.74 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4ENPSR1RXFP1 | |
| SCHEMBL14544643 | 0.74 | MAPT (0.48) | ALDH1A1L3MBTL1KDM4ENPSR1RXFP1 | |
| SCHEMBL14521459 | 0.73 | MAPT (0.46) | ALDH1A1L3MBTL1KDM4ENPSR1RXFP1 | |
| SCHEMBL6055173 | 0.70 | ATM (0.63) | KDM4ENPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |