Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6822148 | 0.88 | MMP2 (0.47) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL6814135 | 0.86 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7715008 | 0.79 | LTA4H (0.55) | NPC1RAB9AALDH1A1KDM4ENPSR1 | |
| SCHEMBL6820163 | 0.74 | LTA4H (0.55) | NPC1RAB9AALDH1A1KDM4ENPSR1 | |
| SCHEMBL6820161 | 0.74 | LTA4H (0.55) | NPC1RAB9AALDH1A1KDM4ENPSR1 | |
| SCHEMBL2179155 | 0.74 | KDM4E (0.51) | MMP2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9185732 | 0.73 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6670868 | 0.72 | MMP9 (0.59) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL1509338 | 0.72 | MMP9 (0.59) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL7355412 | 0.72 | MMP9 (0.59) | MMP2MMP9MMP8MMP12MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |