Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819871 | 0.77 | SRD5A1 (0.55) | OPRM1OPRK1OPRL1SRD5A1NOTUM | |
| SCHEMBL6820061 | 0.75 | SRD5A1 (0.71) | OPRM1OPRK1OPRL1SRD5A1 | |
| SCHEMBL6819941 | 0.72 | SRD5A1 (0.46) | OPRM1OPRK1OPRL1SRD5A1NOTUM | |
| SCHEMBL6815716 | 0.71 | ALDH1A1 (0.41) | SRD5A1NOTUMALDH1A1LMNA | |
| SCHEMBL6746146 | 0.66 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL31469975 | 0.66 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL28230741 | 0.65 | OPRM1 (0.49) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL6815740 | 0.63 | AADAT (0.38) | OPRM1OPRK1OPRL1SRD5A1NOTUM | |
| SCHEMBL181579 | 0.61 | ACHE (0.48) | NOTUMNOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL9372008 | 0.61 | ACHE (0.48) | NOTUMNOS3NOS1NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | claimed |
| US-6723850-B1 | N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-04-20 | — | — | US | disclosed |
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | disclosed |