Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832741 | 0.88 | TDP1 (0.59) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL18782372 | 0.87 | ALDH1A1 (0.64) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL29179309 | 0.85 | ALDH1A1 (0.51) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL1548979 | 0.85 | ALDH1A1 (0.67) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL8130349 | 0.85 | ALDH1A1 (0.54) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL1948309 | 0.85 | ALDH1A1 (0.54) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL26775676 | 0.85 | DHODH (0.56) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL31737536 | 0.85 | ALDH1A1 (0.54) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL1655944 | 0.84 | TDP1 (0.73) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL521687 | 0.83 | ALDH1A1 (0.69) | TDP1ALDH1A1LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127737-A1 | Process for the preparation of carboxylic acid benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-01 | — | — | US | disclosed |
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-18 | — | — | US | disclosed |
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-6600064-B2 | Reacting dibenzyl ethers with alkylcarbonyloxybenzoic or alkoxycarbonyloxybenzoic acids in the presence of one or more acids as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20030055279-A1 | Process for the preparation of benzyl carboxylates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127737-A1 | Process for the preparation of carboxylic acid benzyl esters | CA4, CA7, CA9 | TDP1 4705/4885ALDH1A1 645/4885LMNA 3018/4885 |
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | CPS1, BCAT2, BCAT1 | TDP1 4251/4885ALDH1A1 1490/4885LMNA 2823/4885 |
| US-20030055279-A1 | Process for the preparation of benzyl carboxylates | GABRG2, CA4, NBAS | TDP1 4546/4885ALDH1A1 509/4885LMNA 2910/4885 |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, HACL2 | TDP1 3956/4885ALDH1A1 405/4885LMNA 1868/4885 |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, ALKBH3 | TDP1 3355/4885ALDH1A1 303/4885LMNA 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.