Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352542 | 0.82 | ALDH1A1 (0.47) | TSHRCASP1ACHEALDH1A1CYP3A4 | |
| SCHEMBL1742155 | 0.82 | ACHE (0.58) | TSHRCASP1ACHEPDE10AALDH1A1 | |
| SCHEMBL22133464 | 0.77 | THRB (0.42) | TSHRCASP1ALDH1A1SELLSELP | |
| SCHEMBL10344906 | 0.76 | ALDH1A1 (0.42) | TSHRCASP1ACHEPDE10AALDH1A1 | |
| SCHEMBL17864552 | 0.75 | ACHE (0.65) | TSHRACHEALDH1A1SELLSELP | |
| SCHEMBL5511737 | 0.75 | CA1 (0.36) | TSHRCASP1PDE10AALDH1A1CYP3A4 | |
| SCHEMBL1144151 | 0.75 | CA9 (0.44) | ACHESELLSELPSELECYP3A4 | |
| SCHEMBL9743570 | 0.75 | TSHR (0.52) | TSHRCASP1ACHEPDE10AALDH1A1 | |
| SCHEMBL14087814 | 0.75 | ACHE (0.43) | ACHEALDH1A1SELLSELPSELE | |
| SCHEMBL5306395 | 0.75 | ALDH1A1 (0.41) | TSHRCASP1ACHEPDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636639-A1 | INHIBITORS OF KRAS G12C | Araxes Pharma LLC (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20040255399-A1 | Method and compositions for coloring hair with taurate copolymers | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-12-23 | — | — | US | disclosed |
| US-6146429-A | DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255399-A1 | Method and compositions for coloring hair with taurate copolymers | ADH1A, GRHPR, ADH1C | TSHR 1574/4885CASP1 2650/4885ACHE 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.