Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 9/20 | 0.48 |
| ▸ | DRD4 | P21917 | 6/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841116 | 0.89 | OPRM1 (0.54) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6841059 | 0.89 | OPRM1 (0.57) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6841120 | 0.87 | OPRM1 (0.52) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6842015 | 0.85 | OPRM1 (0.54) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6841698 | 0.84 | PTGDR2 (0.54) | OPRM1PTGDR2DRD2OPRD1MEN1 | |
| SCHEMBL6842012 | 0.83 | OPRM1 (0.60) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6841504 | 0.82 | OPRM1 (0.66) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6842023 | 0.82 | OPRM1 (0.54) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL6425299 | 0.80 | OPRM1 (0.62) | OPRM1DRD3DRD2DRD4OPRD1 | |
| SCHEMBL2221753 | 0.79 | OPRM1 (0.71) | OPRM1DRD3DRD2DRD4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102430-A1 | Drug delivery systems for photodynamic therapy | CHOWDHARY RUBINAH K (CA) | 2004-05-27 | — | — | US | disclosed |
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | SSP CO., LTD. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1325912-A1 | 2,2-DIPHENYLBUTANAMIDE DERIVATIVES AND MEDICINES CONTAINING THE SAME | SSP Co., Ltd. (JP) | 2003-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | OPRD1, OPRM1, OPRK1 | OPRM1 2/4885PTGDR2 127/4885DRD3 95/4885 |
| US-20040102430-A1 | Drug delivery systems for photodynamic therapy | PIN1, PPOX, DHFR | OPRM1 4625/4885PTGDR2 1299/4885DRD3 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.