Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | MMP13 | P45452 | 9/20 | 0.45 |
| ▸ | MMP8 | P22894 | 6/20 | 0.45 |
| ▸ | MMP7 | P09237 | 6/20 | 0.45 |
| ▸ | MMP12 | P39900 | 6/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307793 | 0.85 | ALDH1A1 (0.47) | CA9ALDH1A1TP53HCRTR2 | |
| SCHEMBL5507153 | 0.81 | CA12 (0.47) | CA1CA2CA9ALDH1A1TP53 | |
| SCHEMBL6413208 | 0.80 | MMP3 (0.60) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL8038064 | 0.80 | MMP3 (0.60) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL3693999 | 0.79 | TSHR (0.49) | CA9ALDH1A1HCRTR2 | |
| SCHEMBL27709175 | 0.78 | MMP13 (0.64) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL8411797 | 0.77 | SERPINE1 (0.52) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL8037741 | 0.77 | CNR2 (0.59) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL8038065 | 0.77 | CNR2 (0.59) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL6843429 | 0.77 | CNR2 (0.59) | HDAC3HDAC1HDAC2HDAC6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | NEWTON ROGER SCHOFIELD (US) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | MMP9, TIMP3, MMP3 | HDAC3 265/4885HDAC1 257/4885HDAC2 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.