Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844867 | 0.91 | TSHR (0.32) | — | |
| SCHEMBL6844927 | 0.85 | TARBP2 (0.32) | ALDH1A1 | |
| SCHEMBL6844870 | 0.82 | EGFR (0.38) | ALDH1A1 | |
| SCHEMBL6844919 | 0.80 | POLB (0.34) | ALDH1A1POLB | |
| SCHEMBL6844894 | 0.80 | QRFPR (0.34) | — | |
| SCHEMBL1648329 | 0.78 | CA1 (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6844851 | 0.76 | ALDH1A1 (0.32) | ALDH1A1POLB | |
| SCHEMBL6844879 | 0.76 | POLB (0.36) | ALDH1A1ALOX12HTTPOLB | |
| SCHEMBL6844897 | 0.74 | METAP2 (0.39) | ALDH1A1 | |
| SCHEMBL1648337 | 0.74 | METAP2 (0.43) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |