Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844851 | 0.92 | ALDH1A1 (0.32) | SIRT2ALDH1A1L3MBTL1HTR6 | |
| SCHEMBL6844872 | 0.85 | CA1 (0.36) | ALDH1A1 | |
| SCHEMBL6844919 | 0.81 | POLB (0.34) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6844879 | 0.80 | POLB (0.36) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL1648315 | 0.79 | ALDH1A1 (0.36) | SIRT2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6844894 | 0.78 | QRFPR (0.34) | L3MBTL1 | |
| SCHEMBL6844867 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL6844870 | 0.75 | EGFR (0.38) | ALDH1A1HTR6 | |
| SCHEMBL1648150 | 0.75 | METAP2 (0.44) | — | |
| SCHEMBL6844858 | 0.73 | TSHR (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |