SCHEMBL685004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL686109	0.87	TRPA1 (0.39)	MAPK1NPSR1MEN1KMT2ASMN1; SMN2
	SCHEMBL4260137	0.78	TRPA1 (0.49)	NPSR1MEN1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL686113	0.77	TRPA1 (0.41)	MEN1KMT2ASMN1; SMN2ALDH1A1TRPA1
	SCHEMBL685598	0.76	MAPK1 (0.40)	MAPK1NPSR1MEN1KMT2ASMN1; SMN2
	SCHEMBL685586	0.76	ALDH1A1 (0.44)	NPSR1KMT2AALDH1A1TRPA1MAPT
	SCHEMBL685877	0.76	TRPA1 (0.40)	MEN1KMT2AALDH1A1TRPA1MAPT
	SCHEMBL7643558	0.75	TRPA1 (0.42)	MAPK1ALDH1A1TRPA1MAPTHDAC3
	SCHEMBL685660	0.75	TRPA1 (0.54)	NPSR1MEN1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL23143191	0.74	MAPT (0.47)	MEN1KMT2ASMN1; SMN2ALDH1A1TRPA1
	SCHEMBL685762	0.73	MAPK1 (0.38)	MAPK1NPSR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.