SCHEMBL685598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685674	0.87	RARA (0.42)	MAPK1SMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL685762	0.85	MAPK1 (0.38)	MAPK1NPSR1SMN1; SMN2MEN1KMT2A
	SCHEMBL685672	0.77	EGFR (0.37)	MAPK1KMT2AEGFRPDE4APDE4B
	SCHEMBL685759	0.77	ALDH1A1 (0.38)	SMN1; SMN2MEN1KMT2AALDH1A1EGFR
	SCHEMBL685757	0.77	PDE4A (0.52)	MAPK1NPSR1SMN1; SMN2ALDH1A1PDE4A
	SCHEMBL685595	0.76	TSHR (0.47)	MAPK1SMN1; SMN2MEN1KMT2APDE4A
	SCHEMBL7642683	0.76	TAS1R3 (0.38)	EGFRPDE4APDE4BPDE4CPDE4D
	SCHEMBL685004	0.76	MAPK1 (0.39)	MAPK1NPSR1SMN1; SMN2MEN1KMT2A
	SCHEMBL12040080	0.74	HSP90AA1 (0.43)	ALDH1A1HTTHSP90AA1RARARARB
	SCHEMBL685763	0.72	PTGDR2 (0.42)	SMN1; SMN2KMT2AEGFRMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.