SCHEMBL685877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19923133	0.85	FDPS (0.50)	ALDH1A1MAPTFDPSTSHRMEN1
	SCHEMBL685588	0.84	MAPT (0.38)	TRPA1ALDH1A1MAPTTSHRMEN1
	SCHEMBL4260137	0.83	TRPA1 (0.49)	TRPA1BACE1ALDH1A1HDAC3HDAC4
	SCHEMBL13348559	0.83	TRPA1 (0.53)	TRPA1ALDH1A1FDPSTSHRMEN1
	SCHEMBL685667	0.83	MEN1 (0.39)	TRPA1ALDH1A1MAPTCYP3A4TSHR
	SCHEMBL10415436	0.81	TRPA1 (0.42)	TRPA1ALDH1A1MAPTFDPSTSHR
	SCHEMBL685586	0.81	ALDH1A1 (0.44)	TRPA1ALDH1A1HDAC3HDAC4HDAC1
	SCHEMBL7643558	0.80	TRPA1 (0.42)	TRPA1BACE1ALDH1A1HDAC3HDAC4
	SCHEMBL685660	0.80	TRPA1 (0.54)	TRPA1ALDH1A1MAPTFDPSTSHR
	SCHEMBL23143191	0.79	MAPT (0.47)	TRPA1BACE1ALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.