Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.42 |
| ▸ | DRD3 | P35462 | 9/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131464 | 0.98 | ACHE (0.40) | DRD2DRD3ACHEHRH3SIGMAR1 | |
| SCHEMBL6855118 | 0.89 | HRH3 (0.42) | ACHEHRH3PARP1 | |
| SCHEMBL6850100 | 0.82 | DRD2 (0.40) | DRD2DRD3ACHEHRH3SIGMAR1 | |
| SCHEMBL6858200 | 0.76 | KEAP1 (0.42) | DRD2ACHEHRH3SIGMAR1PARP1 | |
| SCHEMBL9625513 | 0.74 | GBA1 (0.33) | — | |
| SCHEMBL6855141 | 0.70 | KMT2A (0.42) | — | |
| SCHEMBL6858212 | 0.68 | ACHE (0.38) | ACHEPARP1 | |
| SCHEMBL8660652 | 0.67 | — | — | |
| SCHEMBL6849961 | 0.67 | CYP1A2 (0.42) | HRH3 | |
| SCHEMBL13161 | 0.67 | KMT2A (0.58) | DRD2DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |