SCHEMBL685604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685882	0.89	TDP1 (0.47)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL8481868	0.88	CREBBP (0.47)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL685763	0.88	PTGDR2 (0.42)	EGFRHTTSMN1; SMN2MAPTKMT2A
	SCHEMBL20380134	0.81	CHEK1 (0.41)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL12553298	0.79	CA12 (0.57)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL21812227	0.79	NPC1 (0.48)	ALDH1A1HTTSMN1; SMN2MAPTHPGD
	SCHEMBL686110	0.78	MAPT (0.44)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL686119	0.78	TSHR (0.51)	EGFRALDH1A1SMN1; SMN2KDM4EGAA
	SCHEMBL3142232	0.78	ABL1 (0.51)	EGFRCHEK1AURKADAPK3JAK2
	SCHEMBL685759	0.78	ALDH1A1 (0.38)	EGFRALDH1A1HTTSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.