SCHEMBL685667

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685588	0.99	MAPT (0.38)	MEN1KMT2AALDH1A1THRBTHRA
	SCHEMBL685877	0.83	TRPA1 (0.40)	MEN1KMT2AALDH1A1TSHRMAPT
	SCHEMBL685024	0.82	SMPD1 (0.40)	ALDH1A1HTTMAPTL3MBTL1SMN1; SMN2
	SCHEMBL685022	0.81	FDPS (0.41)	ALDH1A1HTTMAPTMAPK1L3MBTL1
	SCHEMBL8702775	0.79	MTNR1A (0.50)	MEN1KMT2AALDH1A1HTR2ATSHR
	SCHEMBL12802075	0.78	TYR (0.46)	MEN1KMT2AALDH1A1THRBTHRA
	SCHEMBL685597	0.77	LTB4R (0.41)	MEN1KMT2AALDH1A1THRBTHRA
	SCHEMBL12802596	0.76	TYR (0.43)	MEN1KMT2AALDH1A1THRBTHRA
	SCHEMBL4260137	0.76	TRPA1 (0.49)	MEN1KMT2AALDH1A1TSHRHTT
	SCHEMBL685027	0.76	LTB4R (0.40)	MEN1KMT2AALDH1A1THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.