SCHEMBL6860439

SCHEMBL6860439

O=C(Br)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
XBP1 P17861 1/20 0.44
CNR2 P34972 1/20 0.42
EPHX1 P07099 1/20 0.42
EPHX2 P34913 1/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
GLA P06280 1/20 0.42
P2RX7 Q99572 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251840 0.77 HSD11B1 (0.50) HSD11B1L3MBTL1GAAMAPTXBP1
Ammonia Solution, Strong SCHEMBL11787415 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1GAAMAPTXBP1
SCHEMBL133056 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1GAAMAPTXBP1
SCHEMBL19557168 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL546352 0.74 HTT (0.48) HSD11B1L3MBTL1GAAMAPTXBP1
SCHEMBL12714 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL19557166 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL11825462 0.74 ALDH1A1 (0.39) HSD11B1L3MBTL1HTTALDH1A1KMT2A
SCHEMBL2672258 0.72 HSD11B1 (0.46) HSD11B1L3MBTL1GAAMAPTXBP1
Hydrochloric Acid SCHEMBL1061147 0.72 L3MBTL1 (0.50) HSD11B1L3MBTL1EPHX1EPHX2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119498288-A Supermolecule hybrid hydrogel with pH responsiveness and preparation method thereof 内蒙古农业大学 2025-02-25 CN disclosed
US-20240368215-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE YOKOGAWA ELECTRIC CORPORATION (JP) 2024-11-07 US disclosed
EP-4458460-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE Yokogawa Electric Corporation (JP) 2024-11-06 EP disclosed
CN-117820192-A Gamma-lactam ring compound and preparation method and application thereof 重庆理工大学 2024-04-05 CN disclosed
CN-101600683-B Therapeutic compounds FIBROTECH THERAPEUTICS PTY LTD AU 2013-06-12 CN disclosed
CN-101600683-A Therapeutic compounds FIBROTECH THERAPEUTICS PTY LTD (AU) 2009-12-09 CN disclosed
CN-1308338-C Phosphorus compound DAICEL CHEM (JP) 2007-04-04 CN disclosed
CN-1224625-C Phosphorus-containing compound DAICEL CHEM (JP) 2005-10-26 CN disclosed
CN-1597686-A Phosphorus compound DAICEL CHEM (JP) 2005-03-23 CN disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed
CN-1383429-A Phosphorus-containing compound DAICEL CHEM (JP) 2002-12-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368215-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE VIP, ANPEP, NPPA HSD11B1 4586/4885L3MBTL1 2268/4885GAA 1322/4885
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 HSD11B1 276/4885L3MBTL1 2587/4885GAA 4674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.