Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192158 | 0.79 | KMT2A (0.42) | MAPTALDH1A1PRKCAPRKCDTP53 | |
| SCHEMBL4640184 | 0.78 | TAS1R3 (0.40) | MAPTTSHRALDH1A1MAPK1TAS1R3 | |
| SCHEMBL4905644 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL28818174 | 0.75 | ALDH1A1 (0.45) | TSHRALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL12965759 | 0.75 | PRKCA (0.50) | MAPTTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL11699744 | 0.74 | KDM4E (0.44) | TSHRALDH1A1MAPK1ACE2KDM4E | |
| SCHEMBL1638386 | 0.74 | LMNA (0.45) | MAPTTSHRALDH1A1POLBPRKCA | |
| SCHEMBL2593871 | 0.71 | TAS1R3 (0.36) | TSHRALDH1A1KDM4EPOLBTAS1R3 | |
| SCHEMBL1638457 | 0.71 | KMT2A (0.40) | MAPTTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL28948581 | 0.69 | SLC37A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777027-B2 | BLEND OF CATIONIC CURABLE RESIN, CATIONIC PHOTOINITIATOR, FREE RADICAL CURABLE RESIN, FREE RADICAL PHOTOINITIATOR; FUSING WITH HEAT AND CURING | ROHM AND HAAS COMPANY | 2004-08-17 | — | — | US | disclosed |
| US-20040067304-A1 | Blend of a free radical curable resin, a cationic curable resin, a free radical photoinitiator and a cationic photoinitiator | ROHM AND HAAS COMPANY | 2004-04-08 | — | — | US | disclosed |