Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KLK3 | P07288 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867019 | 0.81 | DYRK1A (0.47) | F12ADORA2ASMN1; SMN2 | |
| SCHEMBL6871922 | 0.80 | CYP19A1 (0.54) | F12F2KMT2AMAPTKLK7 | |
| SCHEMBL6870753 | 0.79 | ADORA2A (0.37) | ADORA2A | |
| SCHEMBL6867215 | 0.78 | PLAU (0.47) | F2KMT2ACYP1A2HPGDCYP2C19 | |
| SCHEMBL6871512 | 0.77 | KMT2A (0.49) | F12F2KMT2AMAPTCYP1A2 | |
| SCHEMBL6868100 | 0.74 | ADORA2A (0.44) | KMT2AMAPTHPGDADORA2AMEN1 | |
| SCHEMBL6869675 | 0.74 | ALDH1A1 (0.54) | F12F2KMT2AMAPTCYP1A2 | |
| SCHEMBL6869680 | 0.73 | ADORA2A (0.39) | HPGDADORA2ASMN1; SMN2 | |
| SCHEMBL7426447 | 0.70 | ADORA3 (0.46) | F12F2KMT2AMAPTCYP1A2 | |
| SCHEMBL6871681 | 0.70 | ADORA2A (0.51) | F12F2KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |