Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1227449 | 0.88 | LMNA (0.36) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1226946 | 0.86 | ACP3 (0.35) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1227055 | 0.84 | ACP3 (0.34) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL2462792 | 0.81 | SLC6A4 (0.41) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL6873657 | 0.77 | GGPS1 (0.35) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6442055 | 0.75 | PABPC1 (0.43) | LMNA | |
| Perchlorate SCHEMBL6450572 | 0.73 | — | — | |
| SCHEMBL4330742 | 0.72 | MMP8 (0.37) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL6872242 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2263262 | 0.71 | MMP8 (0.36) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040252099-A1 | Displays for high resolution images and methods for producing same | NTERA LIMITED (IE) | 2004-12-16 | — | — | US | claimed |
| EP-1428066-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | Ntera Limited (IE) | 2004-06-16 | — | — | EP | claimed |
| WO-2003001288-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | NTERA LIMITED (IE) | 2003-01-03 | — | — | WO | claimed |
| US-20040252099-A1 | Displays for high resolution images and methods for producing same | NTERA LIMITED (IE) | 2004-12-16 | — | — | US | disclosed |
| EP-1428066-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | Ntera Limited (IE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003001288-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | NTERA LIMITED (IE) | 2003-01-03 | — | — | WO | disclosed |