Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687841 | 0.92 | GAA (0.67) | GAAALDH1A1LMNAHTTL3MBTL1 | |
| Sulfuric Acid SCHEMBL1983733 | 0.83 | CA1 (0.40) | GAACA1CA2ALDH1A1LMNA | |
| SCHEMBL358592 | 0.82 | GAA (0.62) | GAAALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL31090146 | 0.81 | GAA (0.77) | GAACA2ALDH1A1LMNAHTT | |
| SCHEMBL1406166 | 0.81 | GAA (0.61) | GAACA1CA2MMP1MMP2 | |
| Sulfuric Acid SCHEMBL30665190 | 0.79 | TAAR1 (0.63) | GAAMMP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL1808055 | 0.79 | CDC25A (0.51) | CA1CA2ALDH1A1LMNAHTT | |
| SCHEMBL10605085 | 0.79 | GAA (0.54) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL8867396 | 0.78 | GAA (0.67) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL8868058 | 0.78 | ALDH1A1 (0.67) | GAAALDH1A1LMNACYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117883326-A | Composition for relieving hair dyeing stimulus and preparation method and application thereof | 广州环亚化妆品科技股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| EP-1637122-B1 | 2-(Amino or substituted Amino)-3-5-6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2012-02-29 | — | — | EP | claimed |
| US-7695525-B2 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-04-13 | — | — | US | claimed |
| EP-1634572-B1 | Hair dyeing compositions comprising 2-Amino-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE (US) | 2010-04-07 | — | — | EP | claimed |
| US-20080115297-A1 | 2-(Amino or Substituted Amino)-5, 6-Substituted Phenol Compounds, Dyeing Compositions Containing Them, and Use Thereof | BOLTON PHILIP D | 2008-05-22 | — | — | US | claimed |
| US-7341605-B2 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-11 | — | — | US | claimed |
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | claimed |
| US-7226487-B2 | Oxidative dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-05 | — | — | US | claimed |
| EP-1646606-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-19 | — | — | EP | claimed |
| EP-1637122-A1 | 2-(Amino or substituted Amino)-3-5-6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | The Procter & Gamble Company (US) | 2006-03-22 | — | — | EP | claimed |
| EP-1634573-A1 | 2-(Amino or substituted Amino)-5,6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | The Procter and Gamble Company (US) | 2006-03-15 | — | — | EP | claimed |
| EP-1634572-A1 | Hair dyeing compositions comprising 2-(Amino or substituted Amino)-3-5-substituted phenol compounds and use thereof | The Procter and Gamble Company (US) | 2006-03-15 | — | — | EP | claimed |
| WO-2006023438-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-3-5-6-SUBSTITUTED PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023436-A1 | HAIR DYEING COMPOSITIONS COMPRISING 2-(AMINO OR SUBSTITUTED AMINO)-3-5-SUBSTITUTED PHENOL COMPOUNDS AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023435-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5, 6-SUBSTITUTED PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-02-16 | — | — | US | claimed |
| US-20060032001-A1 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2006-02-16 | — | — | US | claimed |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2006-02-16 | — | — | US | claimed |
| WO-2005007615-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-27 | — | — | WO | claimed |
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080115297-A1 | 2-(Amino or Substituted Amino)-5, 6-Substituted Phenol Compounds, Dyeing Compositions Containing Them, and Use Thereof | KRT18, S100A6, S100A4 | GAA 4179/4885CA1 2209/4885CA2 977/4885 |
| US-20060032001-A1 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | KRT18, S100A6, S100A4 | GAA 4179/4885CA1 2209/4885CA2 977/4885 |
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | KRT18, TYR, TH | GAA 4643/4885CA1 3191/4885CA2 1608/4885 |
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | KRT18, LOX, TYR | GAA 3854/4885CA1 2265/4885CA2 909/4885 |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | KRT18, S100A6, S100A4 | GAA 4385/4885CA1 2304/4885CA2 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.