Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933371 | 0.92 | GAA (0.42) | CA2GAAKDM4EALDH1A1ALOX5 | |
| Sulfuric Acid SCHEMBL687450 | 0.83 | GAA (0.57) | CA1CA2CA12CA5ACA9 | |
| SCHEMBL29126270 | 0.80 | PRSS1 (0.50) | CA2GAAKDM4EALDH1A1ALOX5 | |
| SCHEMBL29775051 | 0.80 | PRSS1 (0.50) | CA2GAAKDM4EALDH1A1ALOX5 | |
| SCHEMBL687841 | 0.74 | GAA (0.67) | GAAKDM4EALDH1A1MAPTCYP1A2 | |
| Sulfuric Acid SCHEMBL29558680 | 0.70 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1MAPTNPC1 | |
| Sulfuric Acid SCHEMBL142972 | 0.70 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1MAPTNPC1 | |
| Sulfuric Acid SCHEMBL7132360 | 0.69 | ALDH1A1 (0.54) | GAAKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL12781096 | 0.69 | PRSS1 (0.41) | CA1CA2CA12CA5ACA9 | |
| SCHEMBL4720461 | 0.68 | ALDH1A1 (0.52) | CA1CA2CA12CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7740665-B2 | Single component hair coloring composition | ZOTOS INTERNATIONAL, INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20100064449-A1 | Single component hair coloring composition | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | claimed |
| US-20110318293-A1 | Hair Preparation Comprising Royal Jelly | KLEEN ASTRID (DE) | 2011-12-29 | — | — | US | disclosed |
| EP-1586301-B1 | Process for oxidative colouring keratin fibres with a pre-treatment composition comprising dihydroxyacetone | KPSS KAO GMBH (DE) | 2011-06-29 | — | — | EP | disclosed |
| US-7740665-B2 | Single component hair coloring composition | ZOTOS INTERNATIONAL, INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100064449-A1 | Single component hair coloring composition | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | disclosed |
| US-7306633-B2 | Pre-treatment composition for oxidative coloring keratin fibres and process therefore | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2007-12-11 | — | — | US | disclosed |
| EP-1797863-A1 | Combinations of dye precursors comprising a diaminopyrazole derivative, an m-aminophenol derivative and an m-phenylene diamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-20 | — | — | EP | disclosed |
| EP-1586301-A1 | Pre-treatment composition for oxidative colouring keratin fibres and process therefore | KPSS-Kao Professional Salon Services GmbH (DE) | 2005-10-19 | — | — | EP | disclosed |
| US-20050210606-A1 | Pre-treatment composition for oxidative coloring keratin fibres and process therefore | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1185234-B1 | NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLORANTS | HENKEL KGAA (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6224856-B1 | Means and method for tinting keratin fibers, particularly human hair | WELLA AKTIENGESELLSCHAFT (DE) | 2001-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318293-A1 | Hair Preparation Comprising Royal Jelly | KRT18, CUTA, PLOD3 | SLC6A2 4744/4885CA1 3963/4885CA2 4168/4885 |
| US-20050210606-A1 | Pre-treatment composition for oxidative coloring keratin fibres and process therefore | KRT18, ADH1B, ADH4 | SLC6A2 1677/4885CA1 4545/4885CA2 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.