Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681858 | 0.78 | MAPT (0.46) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL10664892 | 0.76 | ACHE (0.37) | MAPTMAPK1HTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4733026 | 0.76 | MAPT (0.59) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL10247162 | 0.75 | PTPN1 (0.46) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL6245368 | 0.72 | MAPK1 (0.46) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL8882483 | 0.72 | BCHE (0.47) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL9007487 | 0.72 | MAPT (0.80) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL10372977 | 0.72 | L3MBTL1 (0.53) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL4899662 | 0.72 | MAPT (0.49) | MAPTTDP1L3MBTL1MAPK1HTR1A | |
| SCHEMBL17912878 | 0.71 | MAPT (0.66) | MAPTTDP1L3MBTL1MAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040158066-A1 | Novel pyridylmethylaminopyrimidines | ALTANA PHARMA AG (DE) | 2004-08-12 | — | — | US | disclosed |
| EP-1395592-A1 | NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES | ALTANA Pharma AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094831-A1 | NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES | ALTANA PHARMA AG (DE) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158066-A1 | Novel pyridylmethylaminopyrimidines | PGLS, PLPBP, PDXK | MAPT 4312/4885TDP1 2704/4885L3MBTL1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.