Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156063 | 0.88 | ERCC1 (0.40) | ERCC1FEN1ERCC4PIN1KMT2A | |
| SCHEMBL6883598 | 0.87 | TNKS (0.43) | ERCC1FEN1ERCC4PIN1RXFP1 | |
| SCHEMBL6884321 | 0.86 | HSD17B1 (0.44) | ERCC1FEN1ERCC4PIN1RXFP1 | |
| SCHEMBL6883394 | 0.83 | EGLN1 (0.50) | ERCC1FEN1ERCC4PIN1KMT2A | |
| SCHEMBL6885410 | 0.80 | PIN1 (0.60) | ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6885488 | 0.80 | PIN1 (0.47) | ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6884647 | 0.80 | ERCC1 (0.43) | ERCC1FEN1ERCC4PIN1TNKS | |
| SCHEMBL6885301 | 0.80 | PIN1 (0.47) | ERCC1FEN1ERCC4PIN1KMT2A | |
| SCHEMBL6886274 | 0.79 | ALOX5 (0.49) | ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6883583 | 0.79 | ERCC1 (0.44) | ERCC1FEN1ERCC4PIN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | claimed |