Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141068 | 1.00 | LMNA (0.48) | LMNAL3MBTL1CA2ALDH1A1TSHR | |
| SCHEMBL7603166 | 1.00 | LMNA (0.48) | LMNAL3MBTL1CA2ALDH1A1TSHR | |
| SCHEMBL20871102 | 0.78 | RAB9A (0.52) | L3MBTL1CA2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3567649 | 0.78 | NPC1 (0.41) | LMNAL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL12493911 | 0.78 | CA2 (0.50) | LMNAL3MBTL1CA2ALDH1A1TSHR | |
| SCHEMBL3567647 | 0.78 | NPC1 (0.41) | LMNAL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL12493915 | 0.78 | CA2 (0.50) | LMNAL3MBTL1CA2ALDH1A1TSHR | |
| SCHEMBL6893957 | 0.78 | ALDH1A1 (0.56) | LMNAL3MBTL1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7571738 | 0.77 | LMNA (0.48) | LMNAL3MBTL1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12894229 | 0.77 | CA2 (0.48) | LMNAL3MBTL1CA2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066773-B1 | N-(2-(2-AMINO-2-PHENYLETHYL)PHENYL)-2,2-DIMETHYL-PROPANAMID AND DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-05 | — | — | EP | claimed |
| JP-60155114-A | — | — | None | — | — | JP | disclosed |
| JP-63264411-A | — | — | None | — | — | JP | disclosed |
| US-9346772-B2 | Preparation method for an imine compound and reduction method for solid powder of a carbamic acid derivative | Sogang University Research Foundation (KR) | 2016-05-24 | — | — | US | disclosed |
| US-20150344451-A1 | PREPARATION METHOD FOR AN IMINE COMPOUND AND REDUCTION METHOD FOR SOLID POWDER OF A CARBAMIC ACID DERIVATIVE | UNIV SOGANG RES FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
| US-9150498-B2 | Process for the preparation of oseltamivir and methyl 3-epi-shikimate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-06 | — | — | US | disclosed |
| US-9150498-B2 | Process for the preparation of oseltamivir and methyl 3-epi-shikimate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-06 | — | — | US | disclosed |
| US-9126903-B2 | Preparation method for solid powder of a carbamic acid derivative | Sogang University Research Foundation (KR) | 2015-09-08 | — | — | US | disclosed |
| US-20150099886-A1 | PREPARATION METHOD FOR SOLID POWDER OF A CARBAMIC ACID DERIVATIVE | Sogang University Research Foundation (KR) | 2015-04-09 | — | — | US | disclosed |
| US-20140243537-A1 | PROCESS FOR THE PREPARATION OF OSELTAMIVIR AND METHYL 3-EPI-SHIKIMATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-28 | — | — | US | disclosed |
| US-4727149-A | Preparation of nitriles of fused ring pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1988-02-23 | — | — | US | disclosed |
| US-4707552-A | Preparation of nitriles and thioamides of fused ring pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1987-11-17 | — | — | US | disclosed |
| JP-S60155114-A | CARCINOSTATIC AGENT | RIKAGAKU KENKYUSHO | 1985-08-15 | — | — | JP | disclosed |
| US-4517127-A | β-Lactam derivatives and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1985-05-14 | — | — | US | disclosed |
| EP-0066773-B1 | N-(2-(2-AMINO-2-PHENYLETHYL)PHENYL)-2,2-DIMETHYL-PROPANAMID AND DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-05 | — | — | EP | disclosed |
| EP-0111286-A1 | Novel beta-lactam derivatives and process for production thereof | Sanraku Incorporated (JP) | 1984-06-20 | — | — | EP | disclosed |
| EP-0066773-A1 | N-(2-(2-amino-2-phenylethyl)phenyl)-2,2-dimethyl-propanamid and derivatives and a process for preparing the same | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4289905-A | 2-Aza-1,3-dienes | CIBA-GEIGY CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4265784-A | Azine liquid crystal compounds for use in light-control devices | GENERAL ELECTRIC COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4196975-A | Azine liquid crystal compounds for use in light-control devices | GENERAL ELECTRIC COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243537-A1 | PROCESS FOR THE PREPARATION OF OSELTAMIVIR AND METHYL 3-EPI-SHIKIMATE | CYP51A1, CYP2B6, CYP2C8 | LMNA 4533/4885L3MBTL1 2705/4885CA2 1740/4885 |
| US-20150099886-A1 | PREPARATION METHOD FOR SOLID POWDER OF A CARBAMIC ACID DERIVATIVE | CA7, CA2, PGA5 | LMNA 3911/4885L3MBTL1 4143/4885CA2 2/4885 |
| US-20150344451-A1 | PREPARATION METHOD FOR AN IMINE COMPOUND AND REDUCTION METHOD FOR SOLID POWDER OF A CARBAMIC ACID DERIVATIVE | HRH2, C9, PGA5 | LMNA 1558/4885L3MBTL1 4198/4885CA2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.