Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141068 | 0.77 | LMNA (0.48) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL12894229 | 0.77 | CA2 (0.48) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL7603166 | 0.77 | LMNA (0.48) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL9865680 | 0.77 | CA2 (0.48) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL6888679 | 0.77 | LMNA (0.48) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL1101650 | 0.76 | LMNA (0.52) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL3443847 | 0.76 | LMNA (0.52) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL19003736 | 0.76 | LMNA (0.52) | LMNAL3MBTL1CA2G6PC1TAAR1 | |
| SCHEMBL8924551 | 0.76 | L3MBTL1 (0.46) | LMNAL3MBTL1CA2G6PC1RAB9A | |
| SCHEMBL845363 | 0.75 | CA2 (0.61) | LMNAL3MBTL1CA2G6PC1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |