Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397771 | 0.85 | ITGB3 (0.55) | MAOBALOX5PPARGPPARAPPARD | |
| SCHEMBL16634946 | 0.85 | ITGB3 (0.55) | MAOBALOX5PPARGPPARAPPARD | |
| SCHEMBL6474783 | 0.85 | ITGB3 (0.55) | MAOBALOX5PPARGPPARAPPARD | |
| SCHEMBL20693061 | 0.85 | MAOB (0.48) | MAOBALOX5PPARGPPARAPPARD | |
| SCHEMBL18918265 | 0.83 | LTA4H (0.52) | MAOBALOX5PPARGPPARAPPARD | |
| SCHEMBL20693059 | 0.79 | ALOX5 (0.49) | MAOBL3MBTL1ALOX5PPARGPPARA | |
| SCHEMBL6890932 | 0.78 | PSMB1 (0.49) | MAOB | |
| SCHEMBL6890928 | 0.78 | PSMB1 (0.49) | MAOB | |
| SCHEMBL6326103 | 0.77 | REN (0.45) | L3MBTL1 | |
| SCHEMBL6890591 | 0.77 | EPOR (0.52) | MAOBL3MBTL1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737410-B1 | SMOOTH MUSCLE ANTIPROLIFERATION AGENTS; SUCH AS 1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-METHYL-CARBAMOYL)-2 -(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-6265382-B1 | E.G., (S--(R*, R*))-(1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-M ETHYL-CARBAM OYL)-2-(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |