Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 10/20 | 0.42 |
| ▸ | RXRB | P28702 | 9/20 | 0.42 |
| ▸ | RXRG | P48443 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL30620437 | 0.96 | HMGCR (0.44) | HMGCRRXRARXRBRXRGTP53 | |
| SCHEMBL6669640 | 0.80 | CYP1A2 (0.53) | MAPTSMN1; SMN2RARBRARGCYP1A2 | |
| SCHEMBL6669641 | 0.80 | CYP1A2 (0.53) | MAPTSMN1; SMN2RARBRARGCYP1A2 | |
| SCHEMBL6669638 | 0.80 | CYP1A2 (0.53) | MAPTSMN1; SMN2RARBRARGCYP1A2 | |
| SCHEMBL6285732 | 0.78 | HMGCR (0.49) | HMGCRRXRARXRBRXRGTP53 | |
| SCHEMBL6937644 | 0.77 | GABBR2 (0.60) | HMGCRTP53CYP3A4MAPTALOX15 | |
| SCHEMBL9487398 | 0.77 | RPS6KA3 (0.53) | CYP3A4 | |
| SCHEMBL6670817 | 0.72 | TPMT (0.44) | RXRARXRBMAPTSMN1; SMN2 | |
| SCHEMBL6670809 | 0.72 | TPMT (0.44) | RXRARXRBMAPTSMN1; SMN2 | |
| SCHEMBL6670819 | 0.72 | TPMT (0.44) | RXRARXRBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180095042-A1 | Method For Detecting Treated Wood | UNIVERSITY OF SOUTH CAROLINA | 2018-04-05 | — | — | US | disclosed |
| EP-2245123-B1 | METHODS FOR PRODUCING ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS | CHEMTURA CORP (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9402860-B2 | Methods of inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| EP-1962866-B1 | Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same | ROOF MATRIX INC (US) | 2015-03-18 | — | — | EP | disclosed |
| US-8563489-B2 | Alkylated 1,3-benzenediamine compounds and methods for producing same | CHEMTURA CORPORATION (US) | 2013-10-22 | — | — | US | disclosed |
| EP-1542842-B1 | NON-TOXIC HYDROPHOBIC ELASTOMERIC POLYMER CHEMISTRY SYSTEM FOR WOOD PRESERVATION | ROOF MATRIX INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2245123-A2 | ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME | Chemtura Corporation (US) | 2010-11-03 | — | — | EP | disclosed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20090156449-A1 | ALKYLATED 1,3-BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME | LANXESS SOLUTIONS US INC. | 2009-06-18 | — | — | US | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20080253984-A1 | METHODS OF INHIBITING THE GROWTH OF ONYCHOMYCOSIS AND URUSHIOL-INDUCED ALLERGIC CONTACT DERMATITIS | NAIL GENESIS LLC | 2008-10-16 | — | — | US | disclosed |
| EP-1962866-A2 | HYDROPHOBIC ELASTOMERIC POLYMER CHEMISTRY DEVICE FOR INHIBITING THE GROWTH OF ONYCHOMYCOSIS AND URUSHIOL-INDUCED ALLERGIC CONTACT DERMATITIS | Roof Matrix, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20070227399-A1 | COMPOSITIONS AND METHODS FOR THE PRESERVATION OF WOOD | NOVUS INTERNATIONAL INC. (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007062381-A2 | HYDROPHOBIC ELASTOMERIC POLYMER CHEMISTRY DEVICE FOR INHIBITING THE GROWTH OF ONYCHOMYCOSIS AND URUSHIOL-INDUCED ALLERGIC CONTACT DERMATITIS | ROOF MATRIX, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20060216267-A1 | Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis | ROOF MATRIX, INC. | 2006-09-28 | — | — | US | disclosed |
| US-7008997-B2 | Non-toxic hydrophobic elastomeric polymer chemistry system for wood preservation | ROOF MATRIX, INC. (US) | 2006-03-07 | — | — | US | disclosed |
| EP-1542842-A1 | NON-TOXIC HYDROPHOBIC ELASTOMERIC POLYMER CHEMISTRY SYSTEM FOR WOOD PRESERVATION | Roof Matrix, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040147649-A1 | Non-toxic hydrophobic elastomeric polymer chemistry system for wood preservation | EPI HEALTH, LLC | 2004-07-29 | — | — | US | disclosed |
| WO-2004018171-A1 | NON-TOXIC HYDROPHOBIC ELASTOMERIC POLYMER CHEMISTRY SYSTEM FOR WOOD PRESERVATION | ROOF MATRIX, INC. (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2000069943-A1 | POLYUREA COMPOSITION | K & L TECHNOLOGIES, INC. (US) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060216267-A1 | Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis | DPM1, POLR1C, ITCH | HMGCR 4213/4885RXRA 4209/4885RXRB 4342/4885 |
| US-20090156449-A1 | ALKYLATED 1,3-BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME | BBOX1, ABHD5, BRD1 | HMGCR 1439/4885RXRA 1739/4885RXRB 2488/4885 |
| US-20080253984-A1 | METHODS OF INHIBITING THE GROWTH OF ONYCHOMYCOSIS AND URUSHIOL-INDUCED ALLERGIC CONTACT DERMATITIS | DPM1, AOC1, POLR1C | HMGCR 3425/4885RXRA 3946/4885RXRB 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.