Stearic Acid

Stearic Acid

SCHEMBL689938

CCCCCCCCCCCCCCCCCC(=O)O.CN(C)CCC(N)=O

nearest known ligand 0.61

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
FABP4 P15090 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
KMT2A Q03164 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myristic Acid SCHEMBL4244022 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL28996526 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL2858778 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL4239058 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL2860351 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL7783084 0.98 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL5892322 0.93 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL5892272 0.93 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL7784973 0.91 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL7783097 0.87 GPR84 (0.46) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3659580-B1 CLEANSER COMPOSITION KAO CORP (JP) 2025-11-05 EP claimed
US-11628130-B2 Cleanser composition KAO CORPORATION (JP) 2023-04-18 US claimed
CN-110958872-B Cleaning agent composition 花王株式会社 2023-03-14 CN claimed
US-11351100-B2 Hair coloring agent composition SUNNYPLACE CO., LTD. (JP) 2022-06-07 US claimed
CN-109549860-B Preparation method of positively charged liposome and charged liposome J网络公司 2022-06-07 CN claimed
US-20210346267-A1 HAIR COLORING AGENT COMPOSITION SUNNYPLACE CO., LTD. (JP) 2021-11-11 US claimed
US-20210145720-A1 CLEANSER COMPOSITION KAO CORPORATION (JP) 2021-05-20 US claimed
US-11000477-B2 Preparing method for positively-electrified charged niosome, and charged niosome J-NETWORK, INC. (US) 2021-05-11 US claimed
EP-3659580-A1 CLEANSER COMPOSITION Kao Corporation (JP) 2020-06-03 EP claimed
CN-110958872-A Cleaning agent composition 花王株式会社 2020-04-03 CN claimed
WO-2019163530-A1 SECOND PREPARATION FOR HAIR TREATMENT AGENT, AND HAIR TREATMENT AGENT 株式会社マンダム 2019-08-29 WO claimed
EP-3459525-A1 PREPARING METHOD FOR POSITIVELY-ELECTRIFIED CHARGED NIOSOME, AND CHARGED NIOSOME J-Network, Inc. (US) 2019-03-27 EP claimed
EP-2404592-B1 HAIR TREATMENT COMPOSITION SHISEIDO CO LTD (JP) 2018-07-18 EP claimed
US-8273336-B2 Hair treatment composition SHISEIDO COMPANY, LTD. (JP) 2012-09-25 US claimed
US-8187579-B2 Thickening agent AJINOMOTO CO., INC. (JP) 2012-05-29 US claimed
US-20120052032-A1 HAIR TREATMENT COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2012-03-01 US claimed
EP-2404592-A1 HAIR TREATMENT COMPOSITION Shiseido Company, Ltd. (JP) 2012-01-11 EP claimed
US-20090030092-A1 THICKENING AGENT AJINOMOTO CO., INC. (JP) 2009-01-29 US claimed
US-20260139213-A1 CELL DETACHMENT METHOD AND CELL DETACHMENT DEVICE CANON KK (JP) 2026-05-21 US disclosed
WO-2003086384-A1 STABILIZED ASCORBIC ACID DERIVATIVES SHOWA DENKO K. K. (JP) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030092-A1 THICKENING AGENT CUTA, NAAA, ACOT7 GPR84 162/4885PPARG 1104/4885PPARD 2726/4885
US-20120052032-A1 HAIR TREATMENT COMPOSITION POLR1C, SHH, DNMT1 GPR84 1350/4885PPARG 2798/4885PPARD 2919/4885
US-20210145720-A1 CLEANSER COMPOSITION ADH1C, WASHC4, AP2S1 GPR84 694/4885PPARG 1669/4885PPARD 2124/4885
US-20260139213-A1 CELL DETACHMENT METHOD AND CELL DETACHMENT DEVICE EPCAM, CD63, L1CAM GPR84 3259/4885PPARG 4850/4885PPARD 3455/4885
US-11628130-B2 Cleanser composition ADH1C, SMURF1, DEGS1 GPR84 745/4885PPARG 1454/4885PPARD 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.