Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.53 |
| ▸ | WNT3A | P56704 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456641 | 0.83 | MEN1 (0.64) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL28728190 | 0.83 | MEN1 (0.64) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL30089541 | 0.83 | CTNNB1 (0.70) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL29062364 | 0.83 | CTNNB1 (0.70) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL634002 | 0.82 | HPGD (0.59) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL29639747 | 0.82 | HPGD (0.59) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL910158 | 0.82 | HPGD (0.59) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL6934563 | 0.80 | PARP1 (0.62) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL2074442 | 0.80 | ACHE (0.61) | PARP1HDAC8HDAC6HPGDTDP1 | |
| SCHEMBL5883556 | 0.80 | TRPA1 (0.57) | PARP1HDAC8HDAC6HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094823-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-08-11 | — | — | WO | disclosed |