Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.54 |
| ▸ | WNT3A | P56704 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954404 | 1.00 | TRPA1 (0.57) | TRPA1ALDH1A1MAPK1GSK3BHIF1A | |
| SCHEMBL11382023 | 0.85 | CTNNB1 (0.58) | ALDH1A1PARP1CTNNB1WNT3AHDAC8 | |
| SCHEMBL29456641 | 0.83 | MEN1 (0.64) | MAPK1PARP1CTNNB1WNT3AHDAC8 | |
| SCHEMBL28728190 | 0.83 | MEN1 (0.64) | MAPK1PARP1CTNNB1WNT3AHDAC8 | |
| SCHEMBL30089541 | 0.83 | CTNNB1 (0.70) | PARP1CTNNB1WNT3AHDAC8HDAC6 | |
| SCHEMBL29062364 | 0.83 | CTNNB1 (0.70) | PARP1CTNNB1WNT3AHDAC8HDAC6 | |
| SCHEMBL7705580 | 0.82 | CTNNB1 (0.55) | PARP1CTNNB1WNT3AHDAC8HDAC6 | |
| SCHEMBL634002 | 0.82 | HPGD (0.59) | ALDH1A1PARP1CTNNB1WNT3AHDAC8 | |
| SCHEMBL910158 | 0.82 | HPGD (0.59) | PARP1CTNNB1WNT3AHDAC8HDAC6 | |
| SCHEMBL29639747 | 0.82 | HPGD (0.59) | PARP1CTNNB1WNT3AHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-02 | — | — | US | disclosed |
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-02 | — | — | US | disclosed |
| US-20150329501-A1 | SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AND THEIR USE AS FUNGICIDES | BASF SE (DE) | 2015-11-19 | — | — | US | disclosed |
| CN-103449946-B | Preparation method of alpha-monochlorinated ketone compound | UNIV HUANGSHAN | 2015-01-14 | — | — | CN | disclosed |
| CN-103449946-A | Preparation method of alpha-monochlorinated ketone compound | UNIV HUANGSHAN | 2013-12-18 | — | — | CN | disclosed |
| CN-101600700-B | Novel 2-amino oxazolines as TAAR1 ligands for CNS disorders | HOFFMANN LA ROCHE | 2013-08-21 | — | — | CN | disclosed |
| EP-1741693-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS | NAGOYA IND SCIENCE RES INST (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-7960526-B2 | Colorimetric-oxycarbonyl protecting groups for use in organic syntheses | BERRY AND ASSOCIATES, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| CN-1944415-B | Benzo[b]thiophene derivatives and preparing method | TEIJIN PHARMA LTD | 2011-04-13 | — | — | CN | disclosed |
| US-20100249393-A1 | COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES | BERRY AND ASSOCIATES, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-20030105106-A1 | 5-HT receptor ligands and uses thereof | CHIANG PHOEBE (US) | 2003-06-05 | — | — | US | disclosed |
| EP-1276739-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | Bristol-Myers Squibb Company (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2003000663-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000666-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2001081340-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-01 | — | — | WO | disclosed |
| CN-1245487-A | Herbicidal 3-aminocarbonyl-or 3-aminothiocarbonyl-substituted 2-benzoylcyclohexane-1, 3-diones | BASF AG (DE) | 2000-02-23 | — | — | CN | disclosed |
| EP-0493617-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE (-)-2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL | KANEGAFUCHI CHEMICAL IND (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-4631280-A | Pyridazine derivatives having a psychotropic action, and medicaments in which they are present | SANOFI (FR) | 1986-12-23 | — | — | US | disclosed |
| US-4565814-A | Pyridazine derivatives having a psychotropic action and compositions | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |
| US-3988375-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105106-A1 | 5-HT receptor ligands and uses thereof | HTR1A, HTR2A, HTR5A | TRPA1 550/4885ALDH1A1 439/4885MAPK1 3195/4885 |
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | TNNC1, PYGM, GYS1 | TRPA1 4672/4885ALDH1A1 3470/4885MAPK1 4580/4885 |
| US-20100249393-A1 | COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES | RNGTT, OGA, HCCS | TRPA1 4523/4885ALDH1A1 1908/4885MAPK1 1457/4885 |
| US-20150329501-A1 | SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AND THEIR USE AS FUNGICIDES | CYP51A1, CYP4B1, CYP1B1 | TRPA1 1390/4885ALDH1A1 228/4885MAPK1 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.