SCHEMBL6903224

SCHEMBL6903224

O=P(O)(S)OC(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28529710 0.80 CYP2C19 (0.34) CYP2C19LMNA
SCHEMBL6903229 0.70
SCHEMBL28638021 0.70 FDPS (0.35)
SCHEMBL784033 0.64
SCHEMBL10484261 0.62
SCHEMBL4252344 0.60
SCHEMBL3828003 0.60 LMNA (0.39) CYP2C19LMNA
SCHEMBL3244386 0.60 LMNA (0.56) CYP2C19LMNA
SCHEMBL10618528 0.60 PGK1 (0.36) CYP2C19LMNA
SCHEMBL10595209 0.59 CYP2C19 (0.38) CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4866045-A APPLYING LARVICIDE E. I. DU PONT NEMOURS AND COMPANY (US) 1989-09-12 US claimed
US-20200236926-A1 PESTICIDE FORMULATION COMPRISING MFC AS RHEOLOGY MODIFIER AMVAC CHEMICAL CORPORATION 2020-07-30 US disclosed
EP-1315421-B1 ORGANOPHOSPHOROUS COMPOSITIONS BASF CORP (US) 2004-06-02 EP disclosed
US-6566349-B1 Applying blend of the insecticide with fatty acid containing crop oil concentrate for controlling insect populations of the lepidopteran order in crops BASF CORPORATION 2003-05-20 US disclosed
US-4866045-A APPLYING LARVICIDE E. I. DU PONT NEMOURS AND COMPANY (US) 1989-09-12 US disclosed
US-4753931-A Nematicidal tetrachloroethyl phosphorothioate E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-28 US disclosed
EP-0160344-B1 METHOD OF CONTROLLING SOIL PESTS USING A PHOSPHOROTHIOATE COMPOUND SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200236926-A1 PESTICIDE FORMULATION COMPRISING MFC AS RHEOLOGY MODIFIER MFAP1, PFAS, DDT CYP2C19 1271/4885LMNA 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.