Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 3/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906108 | 0.94 | MAPT (0.48) | MAPTCNR2DAOSCN2ANOTUM | |
| SCHEMBL6906868 | 0.83 | MAPT (0.50) | MAPTCNR2DAONOTUMGSK3B | |
| SCHEMBL3265916 | 0.78 | MAPK14 (0.53) | MAPTGSK3BMAPK14MAPK9ALDH1A1 | |
| SCHEMBL29420699 | 0.72 | KIF11 (0.62) | CNR2SCN2ANOTUMALDH1A1MAOB | |
| SCHEMBL307920 | 0.72 | KIF11 (0.62) | CNR2SCN2ANOTUMALDH1A1MAOB | |
| SCHEMBL22978405 | 0.72 | CNR2 (0.53) | MAPTCNR2SCN2AALDH1A1LMNA | |
| SCHEMBL26821704 | 0.70 | KIF11 (0.67) | CNR2SCN2AALDH1A1MAOB | |
| SCHEMBL24106776 | 0.70 | KIF11 (0.67) | CNR2SCN2AALDH1A1MAOB | |
| SCHEMBL18049427 | 0.70 | PTGS2 (0.53) | MAPTCNR2SCN2ANOTUMPIM1 | |
| SCHEMBL29678302 | 0.70 | TSHR (0.58) | SCN2ANOTUMALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673923-B2 | PYRAZOLE AND PYRAZOLONE DERIVATIVES, USEFUL AS RNA POLYMERASE INHIBITORS AND ANTIBIOTICS | TULARIK INC. | 2004-01-06 | — | — | US | disclosed |
| US-20020049205-A1 | Pyrazole antimicrobial agents | AMGEN INC. | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049205-A1 | Pyrazole antimicrobial agents | POLRMT, POLR1C, RNGTT | MAPT 3935/4885CNR2 4550/4885DAO 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.