Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425384 | 0.80 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL156656 | 0.78 | MAOB (0.38) | LMNARAB9ARIPK1 | |
| SCHEMBL1641896 | 0.77 | ALDH1A1 (0.44) | LMNAMAPK1HTT | |
| SCHEMBL2294577 | 0.75 | HDAC1 (0.33) | — | |
| SCHEMBL7490527 | 0.74 | TSHR (0.33) | PTPN1 | |
| SCHEMBL10181509 | 0.73 | EPHX2 (0.35) | CYP4F2CYP4A11LMNAMAPK1HTT | |
| SCHEMBL10181392 | 0.72 | ALOX15 (0.45) | CYP4F2CYP4A11LMNAMAPK1HTT | |
| SCHEMBL2297082 | 0.72 | HDAC1 (0.35) | PRSS1TMPRSS15LMNARAB9A | |
| SCHEMBL10841933 | 0.71 | CTNNB1 (0.33) | PTPN1RIPK1 | |
| SCHEMBL7854576 | 0.71 | L3MBTL1 (0.40) | GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040068141-A1 | Process for the synthesis of trifluorophenylacetic acids | ARMSTRONG JOSEPH D (US) | 2004-04-08 | — | — | US | claimed |
| US-20040068141-A1 | Process for the synthesis of trifluorophenylacetic acids | ARMSTRONG JOSEPH D (US) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068141-A1 | Process for the synthesis of trifluorophenylacetic acids | PCCA, PAH, PFAS | PTPN1 1118/4885CYP4F2 17/4885CYP4A11 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.