Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672615 | 0.86 | MAOA (0.59) | MAOAMAOBTSHRACHEALDH1A1 | |
| SCHEMBL14537388 | 0.83 | MAOA (0.31) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL13495858 | 0.83 | AKR1B1 (0.44) | CYP1A2ALDH1A1CA9HPGDBRD4 | |
| SCHEMBL14048130 | 0.80 | HTR5A (0.31) | ALDH1A1HPGDMEN1KMT2AHTR5A | |
| SCHEMBL11981459 | 0.80 | MAOA (0.38) | MAOAMAOBHTR2CUCK2HTR2A | |
| SCHEMBL8817780 | 0.76 | MAOA (0.41) | MAOAMAOBTSHRCYP3A4ACHE | |
| SCHEMBL10460624 | 0.76 | MAOA (0.47) | MAOAMAOBCYP1A2CYP2A6HPGD | |
| SCHEMBL13839619 | 0.73 | ALDH1A1 (0.35) | MAOAMAOBTSHRACHEALDH1A1 | |
| SCHEMBL257506 | 0.73 | PARP1 (0.52) | CYP1A2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL834241 | 0.73 | ALDH2 (0.37) | TSHRALDH1A1HPGDBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349935-A | Pyrrolidin derivatives | 华领医药技术（上海）有限公司 | 2018-07-31 | — | — | CN | disclosed |
| US-9217006-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-9217006-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-8450501-B2 | Bidentate chiral ligands for use in catalytic asymmetric addition reactions | SOLVIAS AG (CH) | 2013-05-28 | — | — | US | disclosed |
| US-8450501-B2 | Bidentate chiral ligands for use in catalytic asymmetric addition reactions | SOLVIAS AG (CH) | 2013-05-28 | — | — | US | disclosed |
| US-8415488-B2 | Bidentate secondary phosphine oxide chiral ligands for use in asymmetric addition reactions | SOLVIAS AG (CH) | 2013-04-09 | — | — | US | disclosed |
| US-8415488-B2 | Bidentate secondary phosphine oxide chiral ligands for use in asymmetric addition reactions | SOLVIAS AG (CH) | 2013-04-09 | — | — | US | disclosed |
| US-20110309304-A1 | LUMINESCENT SILVER COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110309304-A1 | LUMINESCENT SILVER COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-8058798-B2 | Emissive metal complexes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-11-15 | — | — | US | disclosed |
| EP-2360162-A1 | LUMINESCENT SILVER COMPLEXES | Sumitomo Chemical Company, Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20110108822-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110108822-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110089818-A1 | Emissive metal complexes | NATIONAL SCIENCE FOUNDATION | 2011-04-21 | — | — | US | disclosed |
| WO-2010054728-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |
| US-7612241-B1 | Hydroformylation process | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2009-11-03 | — | — | US | disclosed |
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108822-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | ICMT, ORAI2, EPCAM | MAOA 419/4885MAOB 545/4885CYP1A2 279/4885 |
| US-20110089818-A1 | Emissive metal complexes | AP1M1, AP2M1, AP3M1 | MAOA 1915/4885MAOB 2695/4885CYP1A2 4279/4885 |
| US-20110309304-A1 | LUMINESCENT SILVER COMPLEX | SOD1, AS3MT, GLO1 | MAOA 3577/4885MAOB 4151/4885CYP1A2 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.