Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16299179 | 1.00 | OPRM1 (0.56) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL3263690 | 0.98 | OPRM1 (0.58) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL10687484 | 0.91 | OPRM1 (0.54) | OPRM1HTTMEN1THRBKMT2A | |
| Isopropylamine SCHEMBL9717358 | 0.86 | HTT (0.56) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL10607175 | 0.84 | HTT (0.57) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL7790055 | 0.84 | HTT (0.50) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL10607828 | 0.84 | HTT (0.57) | OPRM1HTTMEN1THRBKMT2A | |
| SCHEMBL24470473 | 0.82 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10912365 | 0.82 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5468946 | 0.82 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566494-B1 | CXCR4 RECEPTOR COMPOUNDS | ACER THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150011466-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS INC (US) | 2015-01-08 | — | — | US | disclosed |
| US-20130210709-A1 | CXCR4 Receptor Compounds | ACER THERAPEUTICS INC. | 2013-08-15 | — | — | US | disclosed |
| WO-2013106437-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2013-07-18 | — | — | WO | disclosed |
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2012-02-02 | — | — | US | disclosed |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
| WO-2011106703-A2 | CXCR4 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2010053546-A2 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | OPRM1 1747/4885HTT 1710/4885MEN1 398/4885 |
| US-20150011466-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | OPRM1 233/4885HTT 2585/4885MEN1 4240/4885 |
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | APLNR, AP1G1, AP2B1 | OPRM1 223/4885HTT 2433/4885MEN1 4292/4885 |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | CXCR5, CXCR1, CCR5 | OPRM1 1105/4885HTT 1943/4885MEN1 3324/4885 |
| US-20130210709-A1 | CXCR4 Receptor Compounds | CXCR4, CXCL12, SDF4 | OPRM1 124/4885HTT 3807/4885MEN1 3835/4885 |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | CRHR1, CRH, CRHR2 | OPRM1 31/4885HTT 804/4885MEN1 4518/4885 |
| US-20160159861-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | OPRM1 233/4885HTT 2585/4885MEN1 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.