Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319510 | 0.82 | AOC2 (0.51) | PSIP1MAPTHSD11B1MAPK1POLB | |
| SCHEMBL23555194 | 0.80 | ALDH1A1 (0.57) | MAPTALDH1A1HTTMAOB | |
| SCHEMBL1939365 | 0.78 | PLCG1 (0.59) | MAPK1POLBALDH1A1MAOB | |
| SCHEMBL23370050 | 0.78 | CA2 (0.52) | POLBALDH1A1HTTMAOB | |
| SCHEMBL6746194 | 0.78 | PSIP1 (0.61) | PSIP1MAPTHSD11B1POLBALDH1A1 | |
| SCHEMBL5859628 | 0.78 | PSIP1 (0.56) | PSIP1MAPTHSD11B1MAPK1POLB | |
| SCHEMBL20604715 | 0.77 | PSIP1 (0.54) | PSIP1MAPTHSD11B1POLBALDH1A1 | |
| SCHEMBL23554972 | 0.77 | CA2 (0.53) | PSIP1MAPTPOLBALDH1A1TP53 | |
| SCHEMBL10782137 | 0.76 | PSIP1 (0.41) | PSIP1MAPTHSD11B1MAPK1ALDH1A1 | |
| SCHEMBL27712718 | 0.76 | PSIP1 (0.41) | PSIP1MAPTHSD11B1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60092232-A | — | — | None | — | — | JP | disclosed |
| JP-60092231-A | — | — | None | — | — | JP | disclosed |
| CN-111808057-B | Suzuki reaction using alpha-O-alkenyl sulfone as electrophile and application thereof | 四川大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-111808089-B | Preparation method of drug eprogliflozin for treating diabetes or derivative thereof | 四川大学华西医院 | 2023-04-11 | — | — | CN | disclosed |
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-106362797-B | Oxalic acid amide ligand and application thereof in copper-catalyzed aryl halide coupling reaction | 浙江中科创越药业有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-111808057-A | Suzuki reaction using alpha-O-alkenylsulfone as electrophile and use thereof | 四川大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808089-A | Preparation method of drug eprogliflozin for treating diabetes or derivative thereof | 四川大学华西医院 | 2020-10-23 | — | — | CN | disclosed |
| CN-1705913-B | Negative cyan violet laser photosensitive composition, image forming material, image forming element and image forming method | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO.,LTD. (JP) | 2011-11-30 | — | — | CN | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| CN-101165593-A | Photosensitive composition and image forming method | MITSUBISHI CHEM CORP (JP) | 2008-04-23 | — | — | CN | disclosed |
| US-7306894-B2 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7306894-B2 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| CN-1705913-A | Negative cyan violet laser photosensitive composition, image forming material, image forming element and image forming method | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
| JP-S6092232-A | NOVEL METHOD FOR SYNTHESIZING VINYL ETHER | OSAKA SODA CO LTD | 1985-05-23 | — | — | JP | disclosed |
| JP-S6092231-A | SYNTHETIC METHOD OF ACETAL | OSAKA SODA CO LTD | 1985-05-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | PSIP1 2296/4885MAPT 2558/4885HSD11B1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.