Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921379 | 0.92 | HTR6 (0.38) | HTR6KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL6919899 | 0.90 | HTR6 (0.43) | HTR6KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL6918823 | 0.85 | AKR1C3 (0.43) | HTR6KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL6821042 | 0.79 | KDM4E (0.45) | HTR6ALDH1A1KDM4EMETTL3METTL14 | |
| SCHEMBL7130815 | 0.77 | ELANE (0.47) | HTR6KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL6917237 | 0.76 | HTR6 (0.39) | HTR6ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL5767300 | 0.73 | HTR6 (0.56) | HTR6METTL3METTL14AKR1C3 | |
| SCHEMBL6919392 | 0.71 | CHRNB2 (0.42) | HTR6KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7063772 | 0.68 | HTR7 (0.45) | HTR6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6821035 | 0.66 | HTR6 (0.52) | HTR6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |