Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918530 | 0.87 | BMP1 (0.34) | BMP1HPGDALDH1A1KDM4ETHRB | |
| SCHEMBL6918534 | 0.87 | BMP1 (0.34) | BMP1HPGDALDH1A1KDM4ETHRB | |
| SCHEMBL7250425 | 0.80 | MMP1 (0.34) | BMP1HPGDALDH1A1KDM4ETHRB | |
| SCHEMBL6801151 | 0.79 | CTSL (0.39) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL6799441 | 0.78 | MEN1 (0.41) | BMP1KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL6806942 | 0.76 | CTSL (0.43) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL6463419 | 0.74 | CTSS (0.48) | KMT2AMEN1FAAHCES1CTSL | |
| SCHEMBL6465141 | 0.74 | CTSS (0.48) | KMT2AMEN1FAAHCES1CTSL | |
| SCHEMBL6468629 | 0.74 | CTSS (0.48) | KMT2AMEN1FAAHCES1CTSL | |
| SCHEMBL6472183 | 0.73 | FAAH (0.48) | KMT2AHPGDMEN1ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730671-B2 | ENZYME INHIBITOR TREATING AUTOIMMUNE DISEASES, ALZHEIMER'S DISEASE, ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-05-04 | — | — | US | disclosed |