SCHEMBL692383

SCHEMBL692383

CCOC(=O)c1cc(=O)[nH][nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 6/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 6/20 0.46
HPGD P15428 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HSD17B10 Q99714 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
NPC1 O15118 3/20 0.45
GAA P10253 2/20 0.45
GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917082 0.79 GPR84 (0.68) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL10346398 0.79 CYP1A2 (0.60) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL7551807 0.77 CYP2C19 (0.56) KMT2AMEN1ALDH1A1MAPTLMNA
Ethyl Acetate SCHEMBL27574425 0.73 ALDH1A1 (0.52) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL1160497 0.72 LMNA (0.55) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL5692504 0.72 CYP2C19 (0.68) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL1255803 0.72 MMP1 (0.69) MMP2
SCHEMBL17992239 0.72 GABRP (0.49) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL29631567 0.72 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL2150729 0.71 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018207-A1 COMPOUNDS FOR TREATING AND/OR PREVENTING HEPATITIS B VIRUS INFECTIONS, PREPARATION METHOD THEREFOR AND USE THEREOF 上海挚盟医药科技有限公司 2021-02-04 WO disclosed
EP-2421501-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP disclosed
US-7988740-B2 Keratin dyeing compositions comprising a radical scavenger and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-08-02 US disclosed
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof NOXELL CORPORATION 2011-02-17 US disclosed
WO-2010123863-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO disclosed
WO-2009130232-A1 PYRAZOLO [1, 5 -A] PYRAZINE DERIVATIVES AS ANTAGONISTS OF V1B RECEPTORS GLAXO GROUP LIMITED (GB) 2009-10-29 WO disclosed
EP-1493593-B1 Thermal transfer recording system having an amorphous dye phase POLAROID CORP (US) 2006-05-31 EP disclosed
EP-1493593-A1 Thermal transfer recording system having an amorphous dye phase Polaroid Corporation (US) 2005-01-05 EP disclosed
EP-1263607-B1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORP (US) 2004-12-01 EP disclosed
US-6537410-B2 Thermal transfer recording system POLAROID CORPORATION 2003-03-25 US disclosed
WO-1991008265-A1 AZO COMPOUNDS AND THEIR USE AS DYES, 1-SULPHO-6-CARBOXYL-AMINO NAPHTHALINE, ITS USE AS A DIAZO COMPONENT AND PROCESS FOR THE PRODUCTION OF THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-13 WO disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
US-5003049-A Fiber-Reactive Dyes for Hydroxy Textiles BASF AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
EP-0183651-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-05-23 EP disclosed
US-4873320-A COLORFASTNESS; FOR COTTON AND CELLULOSE FIBER MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed
US-4847365-A POLYAMIDES, POLYESTERS, OLEFIN POLYMERS CIBA-GEIGY CORPORATION (US) 1989-07-11 US disclosed
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed
EP-0183651-A2 Metal complexes, process for their preparation and their use CIBA-GEIGY AG (CH) 1986-06-04 EP disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4123429-A 1:1 Chromiferous complex azo compounds having a bidentate chelating group and a monofunctional neutral ligand PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof KRT18, LPO, CYB5R3 KMT2A 2020/4885MEN1 4808/4885ALDH1A1 326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.