Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926216 | 0.87 | NR3C1 (0.38) | KDM4EALDH1A1HPGDNPY1RIRAK4 | |
| SCHEMBL6929031 | 0.87 | SLC6A4 (0.40) | KDM4ENPY1RIRAK4ACP1NR3C1 | |
| SCHEMBL6925999 | 0.83 | ACHE (0.43) | NPY1RACP1NR3C1 | |
| SCHEMBL6924891 | 0.82 | DYRK3 (0.40) | DYRK3CLK1CLK2CLK3DYRK1A | |
| SCHEMBL6928523 | 0.80 | NPY1R (0.42) | ALDH1A1DYRK3CLK1CLK2CLK3 | |
| Trifluoroacetic Acid SCHEMBL6928326 | 0.78 | NR3C1 (0.45) | NPY1RACP1NR3C1 | |
| SCHEMBL6923151 | 0.71 | ACP1 (0.47) | KDM4EALDH1A1GAAHPGDNPY1R | |
| SCHEMBL6096772 | 0.70 | TLR7 (0.56) | NPY1R | |
| Hydrochloric Acid SCHEMBL6929408 | 0.69 | TLR7 (0.55) | NPY1R | |
| SCHEMBL6927830 | 0.69 | ADRB2 (0.40) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |