Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929031 | 0.90 | SLC6A4 (0.40) | NR3C1KDM4ENPY1RHTR6IRAK4 | |
| SCHEMBL6929405 | 0.87 | KDM4E (0.42) | NR3C1KDM4EALDH1A1HPGDNPY1R | |
| SCHEMBL6925999 | 0.85 | ACHE (0.43) | NR3C1NPY1RHTR2BHTR6HTR4 | |
| SCHEMBL6927830 | 0.81 | ADRB2 (0.40) | NPY1RADRB2ADRA2AHTR2CAXL | |
| Trifluoroacetic Acid SCHEMBL6928326 | 0.81 | NR3C1 (0.45) | NR3C1NPY1RHTR2BHTR6HTR4 | |
| SCHEMBL6927586 | 0.79 | NPY1R (0.39) | KDM4EALDH1A1NPY1RHTR4MERTK | |
| SCHEMBL10727630 | 0.74 | TLR7 (0.51) | KDM4EALDH1A1HPGDHTR2BLMNA | |
| SCHEMBL10729243 | 0.73 | LMNA (0.44) | KDM4EALDH1A1LMNAHTTTP53 | |
| SCHEMBL6096772 | 0.72 | TLR7 (0.56) | NPY1RHTR2BHTR4MERTKACHE | |
| Hydrochloric Acid SCHEMBL6929408 | 0.72 | TLR7 (0.55) | NPY1RHTR2BHTR4MERTKACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |