Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 17/20 | 0.54 |
| ▸ | MAPT | P10636 | 14/20 | 0.54 |
| ▸ | MEN1 | O00255 | 13/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.54 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 7/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931854 | 0.84 | CASP3 (0.54) | GAAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL6931406 | 0.80 | MAOA (0.54) | MEN1KMT2ARAB9A | |
| SCHEMBL6931346 | 0.79 | CNR1 (0.51) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6931995 | 0.79 | MEN1 (0.46) | GAAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL6930406 | 0.79 | SMN1; SMN2 (0.55) | GAAMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6931563 | 0.76 | RAB9A (0.59) | GAAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11968855 | 0.75 | GAA (0.73) | GAAMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL11054831 | 0.72 | GAA (0.64) | GAAMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6925981 | 0.72 | CA12 (0.51) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6930411 | 0.72 | GAA (0.59) | GAAMAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | WARNER-LAMBERT COMPANY (US) | 2002-10-31 | — | — | US | claimed |
| US-6624196-B2 | Particularly gelatinase A, collagenase-3, and stromelysin-1 and for the treatment of multiple sclerosis, cardiovascular disorders | WARNER-LAMBERT COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-6541521-B1 | Particularly gelatinase A, collagenase-3, and stromelysin-1 | WARNER-LAMBERT COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | WARNER-LAMBERT COMPANY (US) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | MMP1, MMP8, MMP13 | GAA 269/4885MAPT 718/4885MEN1 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.