Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757884 | 0.80 | TP53 (0.48) | SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL6535237 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL7342248 | 0.68 | ALDH1A1 (0.40) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL7342254 | 0.68 | ALDH1A1 (0.40) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL28294340 | 0.67 | KMT2A (0.40) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL18116316 | 0.67 | TSPO (0.53) | TSPOL3MBTL1POLBLMNA | |
| SCHEMBL7345170 | 0.67 | MMP2 (0.40) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL8429495 | 0.67 | LMNA (0.39) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL8429588 | 0.67 | LMNA (0.39) | SMN1; SMN2L3MBTL1POLBLMNAMAPT | |
| SCHEMBL6464595 | 0.67 | ALDH1A1 (0.39) | SMN1; SMN2L3MBTL1POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | Abbott Laboratories (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002064550-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2002-08-22 | — | — | WO | claimed |