Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17003209 | 1.00 | HSD17B10 (0.64) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL8250205 | 0.83 | CYP1A2 (0.55) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL5998675 | 0.83 | L3MBTL1 (0.48) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL17003212 | 0.81 | PRSS1 (0.44) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL6301356 | 0.79 | CYP1A2 (0.47) | HSD17B10CYP1A2CYP2D6SMN1; SMN2MAPT | |
| SCHEMBL2331407 | 0.78 | NR4A2 (0.52) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL17489043 | 0.78 | CYP1A2 (1.00) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL14286180 | 0.78 | CYP1A2 (1.00) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL478673 | 0.78 | TSHR (0.48) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL13398132 | 0.78 | CYP1A2 (0.42) | HSD17B10CYP1A2CYP2D6SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112340-B1 | METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO, AND PRECURSOR OF 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO | STELLA PHARMA CORP (JP) | 2020-07-15 | — | — | EP | claimed |
| US-20150329564-A1 | CHIRAL 4-BORONOPHENYLALANINE (BPA) DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 18F-LABELED BPA USING SAID DERIVATIVE | OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (JP) | 2015-11-19 | — | — | US | claimed |
| EP-2907818-A1 | CHIRAL 4-BORONOPHENYLALANINE (BPA) DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 18F-LABELED BPA USING SAID DERIVATIVE | Stella Pharma Corporation (JP) | 2015-08-19 | — | — | EP | claimed |
| US-8324417-B2 | Process for the preparation of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid and alkyl esters and acid salts thereof | VIROBAY, INC. (US) | 2012-12-04 | — | — | US | claimed |
| WO-2011022429-A2 | PROCESS FOR THE PREPARATION OF (S)-2-AMINO-5-CYCLOPROPYL-4,4-DIFLUOROPENTANOIC ACID AND ALKYL ESTERS AND ACID SALTS THEREOF | VIROBAY, INC. (US) | 2011-02-24 | — | — | WO | claimed |
| US-20110046406-A1 | PROCESS FOR THE PREPARATION OF (S)-2-AMINO-5-CYCLOPROPYL-4,4-DIFLUOROPENTANOIC ACID AND ALKYL ESTERS AND ACID SALTS THEREOF | VIROBAY, INC. (US) | 2011-02-24 | — | — | US | claimed |
| EP-1878720-B1 | Process for preparing chiral bicycloprolinates as intermediates for the preparation of peptidomimetic protease inhibitors | VERTEX PHARMA (US) | 2010-10-06 | — | — | EP | claimed |
| JP-58150551-A | — | — | None | — | — | JP | disclosed |
| US-12435028-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-12371454-B2 | Cyclic peptide compound having Kras inhibitory action | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-07-29 | — | — | US | disclosed |
| US-12336991-B2 | Factor XIIA inhibitors | UNIVERSITY OF LEEDS (GB) | 2025-06-24 | — | — | US | disclosed |
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | GENENTECH, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20240400617-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-12-05 | — | — | US | disclosed |
| US-5506258-A | EXHIBIT AFFINITY FOR THE BIOLOGICAL RECEPTORS OF NEUROPEPTIDES Y, WHICH ARE PRESENT IN THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS | ELF SANOFI (FR) | 1996-04-09 | — | — | US | disclosed |
| WO-1995008550-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-03-30 | — | — | WO | disclosed |
| EP-0614911-A1 | Compounds having a sulfonamide and an amidinegroup, process for preparation and pharmaceutical compositions comprising them | SANOFI (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0536262-A1 | SUBSTITUTED HISTIDINES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0311473-A1 | Fluorinated derivate of amino acids, useful as tensioactive or cotensioactive agents, and preparations for biomedical use containing these derivatives | APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES ATTA (FR) | 1989-04-12 | — | — | EP | disclosed |
| JP-S58150551-A | N-(DIPHENYLMETHYLENE)SERINE AND PREPARATION THEREOF | TORAY IND INC | 1983-09-07 | — | — | JP | disclosed |
| EP-0047516-A1 | Propylamine derivative and process of manufacturing the same | TORAY INDUSTRIES, INC. (JP) | 1982-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046406-A1 | PROCESS FOR THE PREPARATION OF (S)-2-AMINO-5-CYCLOPROPYL-4,4-DIFLUOROPENTANOIC ACID AND ALKYL ESTERS AND ACID SALTS THEREOF | DNPEP, CTRL, CTSS | HSD17B10 2070/4885CYP1A2 1027/4885CYP2D6 704/4885 |
| US-20240400617-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | HSD17B10 4794/4885CYP1A2 4845/4885CYP2D6 4576/4885 |
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | LSS, LPXN, CYP1B1 | HSD17B10 942/4885CYP1A2 61/4885CYP2D6 159/4885 |
| US-12435028-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | UMPS, DHPS, NT5C3B | HSD17B10 1426/4885CYP1A2 1763/4885CYP2D6 272/4885 |
| US-12371454-B2 | Cyclic peptide compound having Kras inhibitory action | KRAS, NRAS, HRAS | HSD17B10 4794/4885CYP1A2 4845/4885CYP2D6 4576/4885 |
| US-12336991-B2 | Factor XIIA inhibitors | F11, F13B, F12 | HSD17B10 1103/4885CYP1A2 213/4885CYP2D6 902/4885 |
| US-20150329564-A1 | CHIRAL 4-BORONOPHENYLALANINE (BPA) DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 18F-LABELED BPA USING SAID DERIVATIVE | FFAR3, BRS3, FSHR | HSD17B10 411/4885CYP1A2 362/4885CYP2D6 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.