Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ITGA1 | P56199 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937623 | 0.81 | FLT1 (0.43) | WDR5POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6941830 | 0.80 | KDM4E (0.30) | MAPTKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL6940841 | 0.80 | KMT2A (0.35) | MAPTKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL6941462 | 0.80 | ALDH1A1 (0.46) | KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL6939748 | 0.79 | AR (0.38) | PGRARMEN1KMT2A | |
| SCHEMBL6937174 | 0.79 | KAT6A (0.46) | — | |
| SCHEMBL6935282 | 0.77 | GSTO1 (0.38) | PGRMAPTKDM4E | |
| SCHEMBL6934900 | 0.77 | LMNA (0.33) | MAPTPOLB | |
| SCHEMBL6937780 | 0.77 | ALDH1A1 (0.41) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL6939756 | 0.77 | GRIN2D (0.33) | MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | claimed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | claimed |
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |