Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940841 | 0.85 | KMT2A (0.35) | GSTO1ALDH1A1ATMKDM4ELMNA | |
| SCHEMBL6941830 | 0.82 | KDM4E (0.30) | ALDH1A1ATMKDM4ELMNAMAPT | |
| SCHEMBL6934900 | 0.82 | LMNA (0.33) | ALDH1A1LMNAMAPT | |
| SCHEMBL6937780 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ATMKDM4E | |
| SCHEMBL6934342 | 0.80 | L3MBTL1 (0.40) | ALDH1A1ATMKDM4ELMNATP53 | |
| SCHEMBL6939756 | 0.79 | GRIN2D (0.33) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL6938457 | 0.79 | BCAT1 (0.35) | ATM | |
| SCHEMBL6937778 | 0.78 | BRD4 (0.41) | ALDH1A1LMNA | |
| SCHEMBL6942103 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TP53MAPT | |
| SCHEMBL6938296 | 0.77 | CA1 (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |