Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.30 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940841 | 0.86 | KMT2A (0.35) | KDM4EMAPTL3MBTL1GRIN2DGRIN3B | |
| SCHEMBL6937780 | 0.82 | ALDH1A1 (0.41) | KDM4EPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6935282 | 0.82 | GSTO1 (0.38) | KDM4EMAPTATMALDH1A1LMNA | |
| SCHEMBL6934900 | 0.82 | LMNA (0.33) | MAPTPOLBALDH1A1LMNA | |
| SCHEMBL6939756 | 0.82 | GRIN2D (0.33) | KDM4EMAPTGRIN2DGRIN3BGRIA1 | |
| SCHEMBL6938457 | 0.82 | BCAT1 (0.35) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6937623 | 0.81 | FLT1 (0.43) | POLBL3MBTL1GRIN2DGRIN3BGRIA1 | |
| SCHEMBL6937778 | 0.81 | BRD4 (0.41) | POLBL3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL6938296 | 0.81 | CA1 (0.42) | POLBTDP1L3MBTL1CA1CA2 | |
| SCHEMBL6937183 | 0.80 | PGR (0.48) | KDM4EMAPTPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |