Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940841 | 0.85 | KMT2A (0.35) | LMNAMAPTALDH1A1 | |
| SCHEMBL6941830 | 0.82 | KDM4E (0.30) | LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL6937780 | 0.82 | ALDH1A1 (0.41) | POLBALDH1A1 | |
| SCHEMBL6935282 | 0.82 | GSTO1 (0.38) | LMNAMAPTALDH1A1 | |
| SCHEMBL6937778 | 0.81 | BRD4 (0.41) | LMNAPOLBTHRBALDH1A1 | |
| SCHEMBL6934342 | 0.80 | L3MBTL1 (0.40) | LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL6939748 | 0.79 | AR (0.38) | LMNA | |
| SCHEMBL6939756 | 0.79 | GRIN2D (0.33) | LMNAMAPTALDH1A1 | |
| SCHEMBL6938457 | 0.79 | BCAT1 (0.35) | THRB | |
| SCHEMBL6942103 | 0.78 | ALDH1A1 (0.40) | MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |