Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236094 | 0.84 | ALOX15 (0.58) | KMT2ASMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL1970068 | 0.82 | NPC1 (0.58) | LMNASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL17552159 | 0.75 | TRPV1 (0.48) | KMT2ALMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12227604 | 0.75 | GDA (0.45) | KMT2ASMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL2623146 | 0.74 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2MEN1MAPK1ALDH1A1 | |
| SCHEMBL442818 | 0.72 | NOS1 (0.45) | KMT2ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12227599 | 0.72 | GDA (0.45) | KMT2ASMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL219477 | 0.71 | GDA (0.62) | KMT2ALMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL1425017 | 0.70 | ADORA2A (0.52) | KMT2ALMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2623145 | 0.69 | ALPL (0.51) | KMT2ALMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573045-B1 | Reporter molecule and RNA target molecule, both carrying a fluorescent or chromogenic group, placed in close proximity to each other; addition of test compound inhibits their binding and increases fluorescence; drug screening | RIBOTARGETS, LTD. (GB) | 2003-06-03 | — | — | US | disclosed |
| EP-1144681-A3 | METHODS AND KITS FOR DISCOVERY OF RNA-BINDING COMPOUNDS | RiboTargets Limited (GB) | 2001-11-28 | — | — | EP | disclosed |
| EP-1144681-A2 | METHODS AND KITS FOR DISCOVERY OF RNA-BINDING COMPOUNDS | RiboTargets Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-1999064625-A2 | METHODS AND KITS FOR DISCOVERY OF RNA-BINDING COMPOUNDS | RIBOTARGETS LIMITED (GB) | 1999-12-16 | — | — | WO | disclosed |