Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970068 | 0.85 | NPC1 (0.58) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12227601 | 0.82 | RAB9A (0.51) | TRPV1MAPTNPC1RAB9ALMNA | |
| SCHEMBL3236094 | 0.81 | ALOX15 (0.58) | TRPV1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL12227604 | 0.76 | GDA (0.45) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6937511 | 0.75 | KMT2A (0.47) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL16573451 | 0.74 | SMN1; SMN2 (0.59) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL12227599 | 0.73 | GDA (0.45) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL28469810 | 0.73 | GDA (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL219477 | 0.72 | GDA (0.62) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL30208590 | 0.71 | TERT (0.38) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060286-A1 | DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS | NIMBLEGEN SYSTEMS GMBH (DE) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060286-A1 | DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS | CRY2, PRXL2A, MGMT | TRPV1 560/4885HCAR2 4270/4885MAPT 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.